macOS
brew install autocyclerlocal Homebrew formula metadata
brew
Tool for generating consensus long-read assemblies for bacterial genomes. Version 0.6.2 via Homebrew; verified 2026-04-14.
install
brew install autocyclerlocal Homebrew formula metadata
overview
Tool for generating consensus long-read assemblies for bacterial genomes
history
Autocycler is a Rust command-line tool for generating consensus long-read bacterial genome assemblies from multiple alternative assemblies.
The GitHub repository was created on 2023-11-10 and the first public GitHub release, v0.1.0, was published on 2024-11-11. The README describes Autocycler as the successor to Trycycler and says most users should prefer Autocycler over Trycycler.
In 2025, Wick, Howden and Stinear published the Autocycler paper in Bioinformatics, giving the project a formal citation path for research use. By 2026 the project had reached v0.6.2, published on 2026-04-14.
Autocycler's adoption path is academic and bioinformatics-oriented: the README asks research users to cite the Bioinformatics paper, the wiki provides workflows for automated and manually curated assemblies, and the installation docs mention Bioconda in addition to pre-built binaries.
Its scope is intentionally narrower than general genome assembly: the wiki says it aims to produce complete bacterial genome assemblies and requires input assemblies that are mostly or ideally all complete.
The wiki describes a multi-step workflow: subsample reads, generate several input assemblies with supported long-read assemblers, compress assemblies into a unitig graph, cluster contigs, trim and resolve clusters, then combine resolved clusters into consensus_assembly.fasta.
For minimal setup, the very quick start points users at a conda environment and an automated Bash pipeline that runs the full process with reads.fastq.gz, thread count and parallel job count.
Autocycler is notable for packaging a modern Rust bioinformatics executable whose usefulness depends on a surrounding toolchain of long-read assemblers. The binary itself is standalone, but real-world workflows often rely on conda environments, Dockerfiles or pipeline scripts to assemble the full stack.
For package databases, it is a good example of a domain-specific CLI where the Homebrew formula exposes only one executable while the official docs point to Bioconda and custom environments for complete scientific workflows.
security posture
narrow executable package without higher-risk signals.
green risk · low confidence · appliance
Before unattended agent use, check whether the tool reads plaintext credentials, writes remote state, publishes artifacts, or shells out to plugins.
executables
| Command | Kind | Exposure | Note |
|---|---|---|---|
autocycler | cli | global executable |
freshness
These signals separate page generation age, package-manager activity, and upstream release comparison. Version lag is warned only when an evidence URL and comparable versions are present.
https://github.com/rrwick/Autocycler
install metadata
| Package key | brew:autocycler |
|---|---|
| Version | 0.6.2 |
| Package manager | Homebrew |
| Package manager page | https://formulae.brew.sh/formula/autocycler |
| Homepage | https://github.com/rrwick/Autocycler |
| Repository | https://github.com/rrwick/Autocycler |
| Upstream docs | https://github.com/rrwick/Autocycler/wiki |
| License | GPL-3.0-or-later |
| Source archive | https://github.com/rrwick/Autocycler/archive/refs/tags/v0.6.2.tar.gz |
| Last updated | 2026-04-14T10:27:47Z |
| Pulse | updated |
| Build dependencies | rust |
| Bottle | available (on arm64_linux, arm64_sequoia, arm64_sonoma, arm64_tahoe, sonoma, x86_64_linux) |
| Homebrew post-install | not defined |
| Service | none declared |
registry facts
| Source Database | Homebrew formula API |
|---|---|
| Tap | homebrew/core |
| Full Name | autocycler |
| Version Scheme | 0 |
| Revision | 0 |
| Head Version | HEAD |
| Bottle Stable Root URL | https://ghcr.io/v2/homebrew/core |
| Deprecated | no |
| Disabled | no |
| Keg Only | no |
| URL Keys |
|
source trail
This page is generated by av-web from the private package SQLite artifact built by scripts/generate-pkg-sqlite.py.
View the package source record on GitHub.