# Install morpheus with Homebrew

Modeling environment for multi-cellular systems biology. Version 2.4.1 via Homebrew; verified 2026-05-19.

## Install

```sh
sudo av install brew:morpheus
```

Additional install commands:

### macOS

- Homebrew (100%):

```sh
brew install morpheus
```

  Evidence: local Homebrew formula metadata

## Package facts

- **Package key:** brew:morpheus
- **Package manager:** Homebrew
- **Package manager page:** <https://formulae.brew.sh/formula/morpheus>
- **Version:** 2.4.1
- **Source summary:** Modeling environment for multi-cellular systems biology
- **Homepage:** <https://morpheus.gitlab.io/>
- **Repository:** <https://gitlab.com/morpheus.lab/morpheus>
- **Upstream docs:** <https://github.com/rnwood/morpheus#readme>
- **License:** BSD-3-Clause
- **Source archive:** <https://gitlab.com/morpheus.lab/morpheus/-/archive/v2.4.1/morpheus-v2.4.1.tar.gz>
- **Last updated:** 2026-05-19T21:33:02Z
- **Generated:** 2026-07-08T18:08:21+00:00

## Executables

- morpheus (cli)
- morpheus-gui (cli)
- morpheus (alias)
- morpheus-gui (alias)

## Dependencies

- boost
- ffmpeg
- graphviz
- libomp
- libtiff
- qt@5

## Build dependencies

- cmake
- doxygen
- ninja

## Uses from macOS

- bzip2
- libxml2

## Install behavior

- Post-install hook: defined
- Bottle: available on arm64_linux, arm64_sequoia, arm64_sonoma, arm64_tahoe, sonoma, x86_64_linux

## Freshness

- Page generated: 2026-07-08
- Package-manager version: 2.4.1
- Package-manager updated: 2026-05-19
- Local data: ok
- Upstream repository: https://morpheus.gitlab.io/
- info: Release/tag comparison is only available for GitHub repositories.
## Project history and usage

Morpheus is a TU Dresden-centered modeling and simulation environment for multiscale and multicellular systems biology. The project page describes it as a tool for coupling ordinary differential equations, partial differential equations, and cellular Potts models in 2D or 3D, with a declarative GUI workflow and a MorpheusML model-description language. The GitLab project credits Jörn Starruß, Justin Bürger, and other TU Dresden contributors.

### Project history

A major milestone for the software was the 2014 Bioinformatics article by Jörn Starruß, Walter de Back, Lutz Brusch, and Andreas Deutsch, which presented Morpheus as a user-friendly environment for integrating cell-based models with ODE and reaction-diffusion systems. The paper emphasized model construction in biological and mathematical terms rather than programming code, plus support for simulation, visualization, archiving, and batch processing.

### How it is used

In practice, Morpheus is used by computational biology researchers and educators to build shareable multicellular models, run simulations, visualize output, and perform parameter scans. Its package-manager role is unusual for Homebrew: it ships both command-line and GUI entry points, making a research desktop application available through a developer-oriented package manager.

### Sources

- <https://formulae.brew.sh/formula/morpheus>
- <https://gitlab.com/morpheus.lab/morpheus>
- <https://morpheus.gitlab.io/>
- <https://morpheus.gitlab.io/publication/2014/01/17/morpheus-a-user-friendly-modeling-environment-for-multiscale-and-multicellular-systems-biology/>


## Security Notes

No matching local secret-handling manifest was found for morpheus. Nucleus package metadata is still published here so future coverage has a stable package URL.


## Source Database Details

- **Source Database:** Homebrew formula API
- **Tap:** homebrew/core
- **Full Name:** morpheus
- **Version Scheme:** 0
- **Revision:** 0
- **Bottle Stable Root URL:** <https://ghcr.io/v2/homebrew/core>
- **Deprecated:** yes
- **Disabled:** no
- **Keg Only:** no
- **URL Keys:** stable


## Related links

- [Terminal utility packages](https://www.automicvault.com/pkg/terminal-utilities/) - Matched terminal and command-line workflow metadata.
- [Text processing packages](https://www.automicvault.com/pkg/text-processing-tools/) - Matched text, document, or structured-data processing metadata.
- [Developer build packages](https://www.automicvault.com/pkg/developer-build-tools/) - Matched build, compiler, generator, or developer workflow metadata.
- [Networking and protocol packages](https://www.automicvault.com/pkg/networking-protocol-tools/) - Matched network, protocol, or remote-service metadata.
- [ffmpeg](https://www.automicvault.com/pkg/brew/ffmpeg/) - Runtime dependency declared by Homebrew.
- [graphviz](https://www.automicvault.com/pkg/brew/graphviz/) - Runtime dependency declared by Homebrew.
- [libtiff](https://www.automicvault.com/pkg/brew/libtiff/) - Runtime dependency declared by Homebrew.
- [qt@5](https://www.automicvault.com/pkg/brew/qt-5/) - Runtime dependency declared by Homebrew.
- [cmake](https://www.automicvault.com/pkg/brew/cmake/) - Build dependency declared by Homebrew.
- [doxygen](https://www.automicvault.com/pkg/brew/doxygen/) - Build dependency declared by Homebrew.
- [ninja](https://www.automicvault.com/pkg/brew/ninja/) - Build dependency declared by Homebrew.
- [allure](https://www.automicvault.com/pkg/brew/allure/) - Shares av.db curated category or tags: cli, developer-tools, testing.
- [artillery](https://www.automicvault.com/pkg/brew/artillery/) - Shares av.db curated category or tags: cli, developer-tools, testing.
- [busted](https://www.automicvault.com/pkg/brew/busted/) - Shares av.db curated category or tags: cli, developer-tools, testing.
- [bzt](https://www.automicvault.com/pkg/brew/bzt/) - Shares av.db curated category or tags: cli, developer-tools, testing.
- [cargo-fuzz](https://www.automicvault.com/pkg/brew/cargo-fuzz/) - Shares av.db curated category or tags: cli, developer-tools, testing.
- [cargo-hack](https://www.automicvault.com/pkg/brew/cargo-hack/) - Shares av.db curated category or tags: cli, developer-tools, testing.
- [cargo-insta](https://www.automicvault.com/pkg/brew/cargo-insta/) - Shares av.db curated category or tags: cli, developer-tools, testing.
- [cargo-nextest](https://www.automicvault.com/pkg/brew/cargo-nextest/) - Shares av.db curated category or tags: cli, developer-tools, testing.
- [msc-generator](https://www.automicvault.com/pkg/brew/msc-generator/) - Local package facts share a topical domain. Shared terms: cli, developer, developer-tools, graphviz.
- [zoroaster](https://www.automicvault.com/pkg/npm/zoroaster/) - Local package facts share a topical domain. Shared terms: cli, developer, developer-tools, testing.
- [html2text](https://www.automicvault.com/pkg/brew/html2text/) - Local package facts share a topical domain. Shared terms: cli, developer, developer-tools, email.

## Combined YAML source

View the package source record on GitHub. [combined/morpheus.yml](https://github.com/automic-vault/db/blob/main/combined/morpheus.yml)


## Sources

- Nucleus package database
- Geiger risk classifier
- package-page enrichment
- curated package history
- package version freshness
- av.db category and tag curation
- package relationship graph
- cross-ecosystem install command graph
