# Install diamond with Homebrew, Nix Accelerated BLAST compatible local sequence aligner. Version 2.2.3 via Homebrew; verified 2026-07-07. ## Install ```sh sudo av install brew:diamond ``` Additional install commands: ### macOS - Homebrew (100%): ```sh brew install diamond ``` Evidence: local Homebrew formula metadata ### Linux - Nix (92%): ```sh nix profile install nixpkgs#diamond ``` Evidence: nixpkgs package indexes: pkgs/by-name/di/diamond/package.nix from https://api.github.com/repos/NixOS/nixpkgs/git/trees/master?recursive=1 ## Package facts - **Package key:** brew:diamond - **Package manager:** Homebrew - **Package manager page:** - **Version:** 2.2.3 - **Source summary:** Accelerated BLAST compatible local sequence aligner - **Homepage:** - **Repository:** - **Upstream docs:** - **License:** GPL-3.0-or-later - **Source archive:** - **Last updated:** 2026-07-07T12:34:31Z - **Generated:** 2026-07-08T07:18:31+00:00 ## Executables - diamond (cli) - diamond (alias) ## Build dependencies - cmake ## Uses from macOS - sqlite ## Install behavior - Post-install hook: not defined - Bottle: available on arm64_linux, arm64_sequoia, arm64_sonoma, arm64_tahoe, sonoma, x86_64_linux ## Freshness - Page generated: 2026-07-08 - Package-manager version: 2.2.3 - Package-manager updated: 2026-07-07 - Local data: ok - Upstream repository: https://github.com/bbuchfink/diamond - Upstream latest detected: v2.2.3 (current) ## Project history and usage DIAMOND is a high-performance sequence aligner for protein and translated DNA searches, positioned as a BLAST-compatible tool for large biological datasets. ### Project history The README says the initial version was developed by Benjamin J. Buchfink at the Huson lab, University of Tuebingen, from 2013 to 2015. Later development continued independently, with support from an EXIST grant in 2018-2019 and the Max Planck Institute for Biology Tuebingen from 2019 to 2024. ### Adoption history DIAMOND's adoption is tied to its promise of much faster BLAST-like protein and translated DNA alignment. The README highlights 100x to 10,000x BLAST speed, low resource requirements, downloads from GitHub releases, Bioconda availability, Galaxy integration, and citation badges. ### How it is used Package users install DIAMOND when they need command-line database creation, protein search, translated DNA search, sequence clustering, taxonomic classification, or BLAST-style tabular, pairwise, and XML outputs. ### Why package nerds care DIAMOND is significant because it is a research-grade bioinformatics workhorse that also behaves like a normal packaged CLI. That combination makes it common in reproducible pipelines, containers, Conda environments, Homebrew installs, and HPC workflows. ### Timeline - 2013-2015: Initial version developed at the Huson lab, University of Tuebingen. - 2015: Original DIAMOND publication cited in the README. - 2021: Sensitive protein alignments at tree-of-life scale publication cited in the README. - 2026: v2.2.2 release published on GitHub. ### Related projects - The README frames DIAMOND as BLAST-compatible and links it to Bioconda and the European Galaxy server for workflow use. ### Sources - - - - ## Security Notes No matching local secret-handling manifest was found for diamond. Nucleus package metadata is still published here so future coverage has a stable package URL. ## Source Database Details - **Source Database:** Homebrew formula API - **Tap:** homebrew/core - **Full Name:** diamond - **Version Scheme:** 0 - **Revision:** 0 - **Bottle Stable Root URL:** - **Deprecated:** no - **Disabled:** no - **Keg Only:** no - **URL Keys:** stable ## Other Package-Manager Records - Nix - diamond: normalized package name match | nixpkgs package indexes: pkgs/by-name/di/diamond/package.nix from https://api.github.com/repos/NixOS/nixpkgs/git/trees/master?recursive=1 ## Related links - [Source-control packages](https://www.automicvault.com/pkg/source-control-tools/) - Belongs to a source-control command family. - [Terminal utility packages](https://www.automicvault.com/pkg/terminal-utilities/) - Matched terminal and command-line workflow metadata. - [Text processing packages](https://www.automicvault.com/pkg/text-processing-tools/) - Matched text, document, or structured-data processing metadata. - [Networking and protocol packages](https://www.automicvault.com/pkg/networking-protocol-tools/) - Matched network, protocol, or remote-service metadata. - [cmake](https://www.automicvault.com/pkg/brew/cmake/) - Build dependency declared by Homebrew. - [proteinortho](https://www.automicvault.com/pkg/brew/proteinortho/) - Popular package that depends on this formula. - [abpoa](https://www.automicvault.com/pkg/brew/abpoa/) - Shares av.db curated category or tags: bioinformatics, cli, science, sequence-alignment. - [mafft](https://www.automicvault.com/pkg/brew/mafft/) - Shares av.db curated category or tags: bioinformatics, cli, science, sequence-alignment. - [minimap2](https://www.automicvault.com/pkg/brew/minimap2/) - Shares av.db curated category or tags: bioinformatics, cli, science, sequence-alignment. - [blast](https://www.automicvault.com/pkg/brew/blast/) - Shares av.db curated category or tags: bioinformatics, cli, science, sequence-alignment. - [bwa](https://www.automicvault.com/pkg/brew/bwa/) - Shares av.db curated category or tags: bioinformatics, cli, science, sequence-alignment. - [hmmer](https://www.automicvault.com/pkg/brew/hmmer/) - Shares av.db curated category or tags: bioinformatics, cli, science, sequence-alignment. - [lastz](https://www.automicvault.com/pkg/brew/lastz/) - Shares av.db curated category or tags: bioinformatics, cli, science, sequence-alignment. - [mummer](https://www.automicvault.com/pkg/brew/mummer/) - Shares av.db curated category or tags: bioinformatics, cli, science, sequence-alignment. ## Combined YAML source View the package source record on GitHub. [combined/diamond.yml](https://github.com/automic-vault/db/blob/main/combined/diamond.yml) ## Sources - Nucleus package database - Geiger risk classifier - package-page enrichment - curated package history - package version freshness - av.db category and tag curation - package relationship graph - external package-manager database matches - cross-ecosystem install command graph